A type of compound from of a number of amino-acid molecule linked together can be regarded as "formed by a reaction of a carboxyl group of amino-acid reacts with the amino-acid groups of another amino-acid with elimination water. The linked b/w amino-acid called peptide bonds".
Many peptide procedure by cell of brain serve as NTM, neuro=-modulators or hormone protein.All peptides are produced from precursor molecules.Peptides are released from all parts of the terminal button into the synaptic cleft by neuron.
Function
Peptides play a primary role in chemical transmitting information in the nervous system and are active in other process of body.
Bio Synthesis
- Peptide from precursor molecules.
- These precursor are broken into pieces by special enzymes.
- Synthesis of peptides takes place in the soma.These chemicals must be delivered to the terminal buttons.
1. Endogenous Opioid
These drugs reduce pain because they have direct effect on the brain.
2. Enkephalins Receptors
Pert, Snowman and Synder (1974) are discovered the localized region which carry the several receptors which respond to Opiate.These receptors are called enkephalos receptors or peptides.
Opiate Receptors
U = (mu, receptors)
D = (delta receptors)
K = (kapra receptors)
Behavioral Effects
- It reduces pain or sensitivity to pain.
- It is involved in species typical behavior.
- It is responsible for regulating / controlling eating.
- It activate thrust (angiotensin peptides).
- It regulates urinary activities of the kidneys.
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